The technology behind AcceleDent® is predicated on the application of cyclic forces to move teeth faster by accelerating the bone remodeling process. Dr. Jeremy Mao conducted the first animal studies in the early 2000’s, which initially served as the foundation of scientific research in this field.
Over time, subsequent studies have been published on accelerated bone remodeling in a variety of animal models, and they have shed light on the biological response at the cellular level. AcceleDent® is the result of technology development and scientific advancement from the outcome of these early scientific studies.
Kopher RA and Mao JJ. Suture growth modulated by the oscillatory component of micromechanical strain. 2003. J. Bone and Min Res. 18 (3) pp. 521-528.
Vij K and Mao JJ. Geometry and cell density of rat craniofacial sutures during early postnatal development and upon in-vivo cyclic loading. 2006. Bone (38) pp. 722-730.
Peptan AI, Lopez A, Kopher RA, Mao JJ. Responses of intramembranous bone and sutures upon in-vivo cyclic tensile and compressive loading. 2008. Bone (42) pp. 432-438.
Nishimura M, Chiba M, Ohashi T, Sato M, Shimizu Y, Igarashi K, Mitani H. Periodontal tissue activation by vibration: Intermittent stimulation by resonance vibration accelerates experimental tooth movement in rats. 2008. Am J Orthod Dentofacial Orthop 133(4) pp. 572-583.
Liu D. Acceleration of Orthodontic Tooth Movement by Mechanical Vibration. 2010 AADR Annual Meeting. Washington, DC.
Liu D. Histomorphometric Study of Orthodontic Tooth Movement under Mechanical Vibration. 2011 AADR General Session. San Diego, CA.
